The Benzamides
Read Online

The Benzamides pharmacology, neurobiology, and clinical aspects

  • 621 Want to read
  • ·
  • 37 Currently reading

Published by Raven Press in New York .
Written in English


  • Benzamide -- Therapeutic use.,
  • Benzamide -- Physiological effect.,
  • Psychoses -- Chemotherapy.,
  • Benzamides.,
  • Tranquilizing agents, Major.

Book details:

Edition Notes

Includes bibliographies and index.

Statementeditors, Michael Stanley, John Rotrosen.
SeriesAdvances in biochemical psychopharmacology ;, v. 35
ContributionsStanley, Michael, Ph. D., Rotrosen, John.
LC ClassificationsRM315 .A4 vol. 35, RC483.5.B45 .A4 vol. 35
The Physical Object
Paginationxii, 209 p. :
Number of Pages209
ID Numbers
Open LibraryOL3492425M
ISBN 100890046395
LC Control Number82012284

Download The Benzamides


  The Benzamides: Pharmacology, Neurobiology and Clinical Aspects. Vol. 35 of Advances in Biochemical Psychopharmacology. The Benzamides: Pharmacology, Neurobiology and Clinical Aspects. Vol. 35 of Advances in Biochemical PsychopharmacologyAuthor: Peter Tyrer. Benzamides aa 25 Table Schwartz Reduction of DoM-Derived Benzamides and Naphthamides aa 28 Table Amide Substituent Effects on the Facility of Benzamide Reduction by the Schwartz Reagent 30 Table Reductive Cleavage of Indole and Benzimidazole N-Amides aa Using the Schwartz Reagent Advances in the Biosciences, Volume Receptors as Supramolecular Entities exemplifies the concept of transmitter and cotransmitter interactions using GABA receptor as a model. The book contains papers on the interaction of sulpiride and other substituted benzamides with dopamine receptors where the result of receptor stimulation is not a stimulation of cyclic AMP formation.

Our data have shown that nicotinamide and two N-substituted benzamides, metoclopramide (MCA) and 3-chloroprocainamide (3-CPA), gave dose dependent inhibition of lipopolysacharide induced TNF alpha in the mouse within the dose range of mg/kg. Moreover, lung edema was prevented in the rat by 3 × 50 mg/kg doses of 3-CPA or MCA, and John H. MacMillan Department of Chemistry Temple University Philadelphia, Pa. 4-(transPropylcyclohexyl)benzamide,4-(transPentylcyclohexyl)benzamide,and 4-(transHeptylcyclohexyl)benzamide are smoothly converted in high yields to the corresponding methyl carbamates by warming with bromine in dry method is applicable to all alkyl or aryl substituted benzamides.   The benzamide chromophore is widely used as a Cottonogenic derivative of primary amines for stereochemical studies by circular dichroism. The assignments based on the exciton chirality method are reliable since the benzamide group has well-defined geometry and conformation. A recent report (J.D. Chisholm, J. Golik, B. Krishnan, J.A. Matson, D.L. Van Vranken, J. Am. Chem. Soc. . The percutaneous absorption of the fragrances benzyl acetate and five other benzyl derivatives (benzyl alcohol, benzyl benzoate, benzamide, benzoin and benzophenone) was determined in vivo in tion through occluded skin was high for all compounds (approximately 70% of the applied dose in 24 hr) and no significant differences between values for the different compounds were .

(DHQD)2PHAL catalyzed enantioselective chlorocyclization of indoleyl-benzamides was realized. Fused indolines containing a continuous quaternary carbon center and tertiary carbon center were obtained in good yields with excellent enantioselectivity (up to 98% yield and >99% ee). The substituted benzamides, (±)-sultopride and S-(−)-sulpiride and the butyrophenone derivative, haloperidol, were also fairly potent displacers of binding. [ 3 H]-sulpiride binding showed a marked stereospecificity towards neuroleptics, thus (+)-butaclamol was more t times more active than the pharmacologically inactive. Benzamides—Advances in Research and Application: Edition: ScholarlyBrief - Ebook written by Q. Ashton Acton, PhD. Read this book using Google Play Books app on your PC, android, iOS devices. Download for offline reading, highlight, bookmark or take notes while you read Benzamides—Advances in Research and Application: Edition: ScholarlyBrief. PDF | On May 1, , Peter Tyrer published The Benzamides: Pharmacology, Neurobiology and Clinical Aspects. Vol. 35 of Advances in Biochemical Psychopharmacology | Find, read and cite all the.